![]() ![]() ![]() Scrub typhus, caused by the bacteria Orientia tsutsugamushi and transmitted by Leptotrombidium mites, is responsible for a potentially fatal tropical infection which is a grossly under-recognized public health problem in India. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the manuscript and its Supporting Information files.įunding: This work was supported by Wellcome Trust/DBT India Alliance fellowship (IA/CPHS/79) to GMV. Received: MaAccepted: JPublished: July 27, 2021Ĭopyright: © 2021 Devasagayam et al. Improving awareness about this disease, increasing access to testing and initiating appropriate therapy early can help reduce this public health threat in the future.Ĭitation: Devasagayam E, Dayanand D, Kundu D, Kamath MS, Kirubakaran R, Varghese GM (2021) The burden of scrub typhus in India: A systematic review. ![]() This increases complications and the risk of death. In this review, we found that scrub typhus is very common in India and affects multiple organs in the majority of positively tested patients. The insights provided from this review will further enable policymakers to establish a surveillance system to observe this disease and initiate strategies to effectively control, and prevent the spread of, this neglected disease. It also intends to summarize the diagnostic tests that are most commonly used to confirm scrub typhus cases and to map the distribution of cases across India. This systematic review aims to integrate data obtained from medical literature over the past 10 years to estimate the burden of scrub typhus in India. ![]() However, it is a largely overlooked public health problem in India. Scrub typhus has re-emerged as one of the most common life-threatening rickettsial infections accounting for a million cases annually. Scrub typhus is an infection that is caused by a rickettsial bacteria called Orientia tsutsugamushi and transmitted to humans through chigger mites. ![]()
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